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Sigma
Benzidine dihydrochloride
B3383 -
≥99% (titration)
DOWNLOAD MSDS (PDF)Synonym: 4,4′-Diaminobiphenyl dihydrochloride
CAS Number: 531-85-1
Empirical Formula (Hill Notation): C12H12N2 · 2HCl
Molecular Weight: 257.16
Beilstein Registry Number: 3914846
EC Number: 208-519-6
MDL number: MFCD00040389
PubChem Substance ID: 24891713
Properties
| Related Categories | B, Stains & Dyes, A to Z, Stains and Dyes |
| assay | ≥99% (titration) |
| concentration | .08-1.2 mg/mL (lot-specific value provided) |
Description
Biochem/physiol Actions
Tumor initiator in mammary glands of experimental animal.1
Warning
Cancer suspect agent.
Price and Availability
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Safety Information
| Symbol |    GHS07, GHS08, GHS09 |
| Signal word | Danger |
| Hazard statements | H302-H350-H410 |
| Precautionary statements | P201-P273-P308 + P313-P501 |
| Personal Protective Equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
| Hazard Codes | T,N |
| Risk Statements | 45-22-50/53 |
| Safety Statements | 53-45-60-61 |
| RIDADR | UN 2811 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | DD0600000 |
Technical information & documentation associated with this product is available in the Safety & Documentation tab.
Articles
Carcinogenesis and Epigenetics
Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
Vicki Caligur
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Transcription, transformation
References
1. Morton, K.C. et al., Carcinogenicity of benzidine, n,n'-diacetylbenzidine, and n-hydroxy-n,n'-diacetylbenzidine for femal cd rats. Carcinogenesis 2, 747-752, (1981) Abstract
Beil. 13,IV,365
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